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Lung-MAP Precision Medicine Trial Expands To Include More Patients
The Lung Cancer Master Protocol (Lung-MAP), the first precision medicine trial in lung cancer supported by the National Cancer Institute (NCI), part of the National Institutes of Health, is undergoing a major expansion to include patients with all non-small cell lung cancers -- which make up about 85% of all lung cancer diagnoses in the U.S.
The trial previously tested treatments for people with advanced stage squamous cell lung cancer. Opening the trial to all types of advanced stage non-small cell lung cancers means that thousands of new patients will be eligible to enroll in this landmark trial and benefit by taking new investigational drugs to fight their cancer.
"We have more than 200,000 new cases of non-small cell lung cancer in the United States each year, and we desperately need new treatments," said Lung-MAP principal investigator Dr. Vali Papadimitrakopoulou, chief of thorac
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Asthma Pill Targets Airway Muscles To Decrease Attacks
Results from a phase II clinical trial, experimental work on cells and computational modelling have together shown why the first pill for asthma in 20 years can help reduce asthma attacks.
Researchers from Leicester (UK) and Vancouver (Canada) have shown that the investigational drug, Fevipiprant (an oral, selective prostaglandin D2 receptor antagonist), reduces the amount of smooth muscle in the airway lining. The findings are published in Science Translational Medicine.
Professor Chris Brightling, a consultant respiratory physician at Leicester's Hospitals and professor of respiratory medicine at the University of Leicester, said: "Our research shows for the first time that Fevipiprant not only reduces inflammation in the airways, but also reduces the amount of muscle in the lining of the airway. This is likely to explain some of the effects seen in the symptoms and breathing tests f
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Electronic Tool Has Potential To Improve Asthma Care, Study Finds
A new electronic decision support tool for managing asthma has the potential to improve the quality of asthma care in primary care settings, suggests a study led by St. Michael's Hospital in Toronto, Canada.
The research, published today in the European Respiratory Journal, aimed to determine whether the Electronic Asthma Management System (eAMS) could help close existing gaps in asthma care. The system is a first-of-its-kind evidence-based computerized decision support tool.
"We have excellent therapies for this disease, yet most patients do not receive the best care, and as a result, are poorly controlled," said Dr. Samir Gupta, an associate scientist at the Li Ka Shing Knowledge Institute of St. Michael's Hospital, who led this study. "There are many barriers facing busy primary care physicians in providing the best care, including lack of time, knowledge, training, and local resour
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Boy Scout Motto – Be Prepared – Works For Parents Of Campers With Allergies And Asthma
The idea of summer camp looms large for many kids who wonder: Will I make any friends? What if I get lost in the woods? And for campers with allergies and asthma, “What if I have an allergic reaction or an asthma attack?”
“When kids head off to summer camp, especially for the first time, they have lots of questions,” says allergist Todd Mahr, president of the American College of Allergy, Asthma and Immunology (ACAAI). “Kids who suffer from seasonal allergies, food allergies or asthma, also wonder about their health. For them, additional preparation is necessary to keep them safe and happy, so they can enjoy their time away from home.”
If you’re considering camp for your child with allergies or asthma, start planning now to make sure all details are buttoned up before camp begins. Below are five tips from ACAAI to help you and your child enjoy their summer camp experience.