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Vaping-Related Disease: A Challenge For Health Care Providers
The recent emergence of severe and even fatal vaping-related lung disease presents a challenge for health care providers, according to Sanjay Sethi, MD, professor and chief of the division of pulmonary, critical care and sleep medicine in the Department of Medicine in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo.
Sethi is an expert on lung disease, especially chronic obstructive pulmonary disease (COPD) and the respiratory effects of smoking and vaping. He has always been concerned about the potential toxicity of vaping-related lung disease in his practice at UBMD Internal Medicine, and he noted that the rising incidence is now causing some changes in the practice of health care providers.
“Because of the incidence of vaping-related lung disease, it’s now recommended that we ask individuals who come in with respiratory complaints about their vapin
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More Severe OSA Leads To Higher Blood Pressure In Patients With Resistant Hypertension
In patients with high blood pressure resistant to treatment who also have obstructive sleep apnea (OSA), the more severe their OSA, the higher their blood pressure, according to new research published online in the Annals of the American Thoracic Society.
In “Prevalence, Characteristics and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension,” Esther Sapiña-Beltrán and colleagues report on a study conducted in 284 patients, ages 18 to 75, who were treated at hospitals in three countries—Spain, Singapore and Brazil—for resistant hypertension (RH). Of all patients with high blood pressure, those with RH, which requires three or more drugs to control, are at greatest risk for a heart attack or other cardiovascular event.
“We believe that OSA plays an important role in the pathogenesis and prognosis of patients with resistant hypertens
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Researchers Discover New Drug Target For The Fatal Lung Disease PAH
Scientists have identified a molecular pathway that contributes to the development of pulmonary arterial hypertension (PAH), a severe, often fatal condition that has no cure.
The discovery, published Sept. 12, 2019, in Nature Communications, suggests a new target for developing new drug therapies for PAH, according to researchers at Cincinnati Children’s Hospital Medical Center.
What is PAH?
This progressive disease is characterized by high blood pressure in the lungs, and affects adults and children. When left untreated, PAH can lead to fatal heart damage.
Scientists have long known that a process called vascular remodeling drives the thickening of lung arteries that contributes to the increased pressure. Reversing vascular remodeling could be curative.
“PAH is a life-threatening disease in adults and can also complicate the repair of congenital heart disease in children,” Hegde sa
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One-Third Of Young Children Admitted To Intensive Care For Sepsis Show PTSD Symptoms Years Later
Doctors have found that children who have been in Intensive Care Units (ICUs) for sepsis have a significantly increased risk of Post-Traumatic Stress Disorder (PTSD), with around 1/3 showing PTSD symptoms. In some young people, these may persist for years following discharge. There is some evidence that these children have altered immune responses during their stay in ICU and this may be a risk factor for later PTSD symptom development, but this needs to be confirmed.
Sepsis is a potentially life-threatening condition caused by the body's immune system reacting to overwhelming to infection. It can lead to septic shock, damage to major organs, a rapid and potentially fatal blood pressure drop, and needs immediate hospital treatment.
Between 2010 and 2017, researchers from St Mary's Hospital and Imperial College in London followed up 69 young patients (all older than 3 years, average age