Login / Register


Password: [Lost?]

New User? Click here for your FREE subscription

Healthcare Professionals
Healthcare Professionals Healthcare Professionals

Follow Us

NEWS-Line on Twitter NEWS-Line on Facebook NEWS-Line on Google+ NEWS-Line on LinkedIn NEWS-Line on Pinterest

Healthcare Conferences &
Educational Opportunities

Dec. 8 - 12

ASHP Midyear Clinical Meeting

American Society of Health-System Pharmacists

June 14, 2020 - 17, 2020

NADONA's 33rd Annual Conference


July 10, 2020 - 12, 2020

ASHA Connect 2020

American Speech-Language-Hearing Association

Nov. 19, 2020 - 21, 2020

ASHA Convention 2020

American Speech-Language-Hearing Association

More Events

UVA Leads Major Effort To Understand Autism Differences In Boys, Girls | NEWS-Line for Healthcare Professionals

UVA Leads Major Effort To Understand Autism Differences In Boys, Girls


A pioneering autism researcher at the University of Virginia School of Medicine is spearheading an ambitious effort to understand how autism-spectrum disorders differ in boys and girls as part of the National Institutes of Health’s Autism Centers of Excellence Program.

Kevin Pelphrey, PhD, of UVA’s Department of Neurology, and a coalition of scientists at UVA and other top institutions are taking a multi-pronged approach to understanding a great mystery of autism: Why are four times more boys diagnosed with the condition than girls? The lack of information about autism’s manifestation in girls means many are never diagnosed and miss out on beneficial interventions, Pelphrey fears.

The researchers, including experts at UVA’s Curry School of Education, are following children over the course of many years, all the way to adulthood. They hope their research will shed light on autism-spectrum disorders (ASD), which affect one in 59 children, and also identify the best interventions for both girls and boys.

“Our goals include providing a much better understanding of the differences in how autism manifests in girls versus boys,” Pelphrey said. “We want to use the knowledge we gain to help us get the right treatment to the right individual at the right time.”

Differences in Boys and Girls

Pelphrey, Harrison-Wood Jefferson Scholars Foundation professor at UVA, uses high-tech brain scans to illuminate our understanding of ASD, but his research project goes far beyond that. Pelphrey and his collaborators are taking a four-pronged approach that:

Identifies sex differences in brain development in children with ASD;
Uses gene sequencing to link gene variations with degree of brain abnormality;
Uses those findings to predict children’s outcomes in adolescence and young adulthood;

And validates those findings via collaboration with people with ASD.
The researchers hope to facilitate the transition into adulthood for people with ASD.

Shedding light on ASD in girls is of particular importance, as that is an area of research that has been almost entirely overlooked, Pelphrey said.

“Our approach has the advantage of understanding how autism emerges out of interactions between genetic differences, changes in neural circuity and differences in thinking and acting,” Pelphrey said. “This better captures the complex and developmental nature of autism-spectrum disorders.”

Pelphrey and his colleagues have already published dozens of peer-reviewed scientific papers that shed important light on autism as part of their research collaboration. And they are excited about what discoveries lie ahead.

About the Autism Centers of Excellence Program

The research is supported by the National Institutes of Health’s Autism Centers of Excellence Program, grant R01MH100028. The program backs large, multidisciplinary studies that aim to determine the causes of autism and identify potential treatments.

Pelphrey holds joint appointments in the School of Medicine and UVA’s Curry School of Education. He is part of UVA’s Brain Institute, a university-wide effort to accelerate and enhance brain research.

Pelphrey’s recruitment to UVA was facilitated, in part, by the Jefferson Scholars Foundation, a group dedicated to attracting extraordinary minds who possess the highest qualities of leadership, scholarship and citizenship. UVA’s Curry School also played an important role in bringing him to UVA.

To keep up with the latest medical research news from UVA, subscribe to the Making of Medicine blog at http://makingofmedicine.virginia.edu.

Source:University of Virginia Health System

Photo Credit:Dan Addison | UVA

Pictured:Kevin Pelphrey, PhD, of the University of Virginia School of Medicine, is leading a major autism initiative that seeks to shed light on the differences in autism in boys and girls.

Post not cached because it doesn't exist

Share This!

Healthcare Jobs


Exeter, New Hampshire

Physical Therapist

The Orthopaedic Institute
Lake City, Florida

Clinical Assistant/Associate Professor, Pediatrics-General

Stony Brook University
Stony Brook, NY

Assistant Nurse Manager – Adolescent Inpatient Unit

Four Winds Hospital
Katonah, New York

Mental Health Therapist

Tarzana Treatment Centers
Tarzana, CA

Nurse Manager

San Jose, CA

More Jobs
(Dismiss) Thank you for visiting NEWS-Line! Please sign up, login, or follow us on your favorite social networks
to receive custom tailored eNews, job listings, and educational opportunities for your specific profession.