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How To Identify Drugs That Work Best For Each Patient

More than 100 drugs have been approved to treat cancer, but predicting which ones will help a particular patient is an inexact science at best.

A new device developed at MIT may change that. The implantable device, about the size of the grain of rice, can carry small doses of up to 30 different drugs. After implanting it in a tumor and letting the drugs diffuse into the tissue, researchers can measure how effectively each one kills the patient’s cancer cells.

Such a device could eliminate much of the guesswork now involved in choosing cancer treatments, says Oliver Jonas, a postdoc at MIT’s Koch Institute for Integrative Cancer Research and lead author of a paper describing the device in the issue of Science Translational Medicine.

Kentucky Health Center Celebrates A Decade Of Caring For Racetrack Workers

Convincing capricious half-ton racehorses to do your will can take a toll on the human body. The grooms, hotwalkers, exercise riders and other backside workers who tend to the needs of elite Thoroughbred athletes also carry heavy buckets and bales, endure challenging weather conditions, and often travel with the horses to racing meets around the country, making consistent health care difficult.

For 10 years, the University of Louisville School of Nursing, in partnership with the Kentucky Racing Health and Welfare Fund (KRHWF), has provided free or low-cost health-care services to backside workers at the Kentucky Racing Health Services Center (KRHSC), located just across the street from Churchill Downs.

Transgender Adults Start As Transgender Kids

Transgender adults start out as transgender youth. “Kids and parents often come to see me in tremendous distress,” says Johanna Olson, MD, director of the Center for Transyouth Health and Development at Children’s Hospital Los Angeles. “My job as a pediatrician is to help transgender kids move from ‘survive’ to ‘thrive’.”

Until quite recently, it was only possible to undergo a physical gender ‘transition’ as an adult. Medical intervention available for transgender individuals changed in 2006 when Dutch investigators published a paper that described a protocol for using hormone blockers to treat gender identity dysphoria in adolescents.

“We know that going through the ‘wrong’ puberty can be extremely damaging for many of these kids,” says Olson. “The risk of suicide is incredibly high. With hormone blockers – drugs that have safely been used in other contexts for a very long time – we can hit the ‘pause’ button on puberty.”

This Is Your Teen’s Brain Behind The Wheel

A new study of teenagers an d their moms reveals how adolescent brains negotiate risk — and the factors that modulate their risk-taking behind the wheel.

In the study, reported in the journal Social Cognitive and Affective Neuroscience, 14-year-old subjects completed a simulated driving task while researchers tracked blood flow in their brains. In one trial, the teen driver was alone; in another, the teen’s mother was present and watching, said University of Illinois psychology professor Eva Telzer , who led the study.

Laurence Steinberg, a professor of psychology at Temple University, developed the driving task and evaluated how the presence of peers influenced teen risk-taking, Telzer said.

Most Americans Say Medical Marijuana Shouldn’t Be Used By Kids Or In Front Of Kids – Legal Or Not

Medical marijuana and children don’t mix, most Americans say.

While nearly two-thirds of people agree that their state should allow medical marijuana for adults, half as many – just over a third – say it should be allowed for children, according to today’s University of Michigan C.S. Mott Children’s Hospital National Poll on Children’s Health that included a national sample of adults in the US.

Eighty percent of respondents go even further, saying adults shouldn’t be allowed to use medical marijuana in front of kids – a view most prominent among parents of children under 18 years old.

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