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Archive for the ‘Lab’ Category

Cancer Stem Cells Linked To Drug Resistance

Some lung cancer cells become resistant to drugs. Researchers identified an existing drug that reverses stem cell-like properties of tumors, resensitizing them to drug.
Source: UC San Diego School of Medicine

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like [...]

National DNA Day Is April 25; Experts Available For Comment

Friday, April 25, is National DNA Day, the date which commemorates completion of the Human Genome Project, the national effort to identify and decode all 6 billion letters in human DNA. Since that time, medical researchers and practitioners have found new ways to apply genomics for everyone who needs healing, and thanks to staggering technological [...]

Regenerating Muscle In Duchenne Muscular Dystrophy: Age Matters

A team of scientists led by Pier Lorenzo Puri, MD, associate professor at Sanford-Burnham Medical Research Institute (Sanford-Burnham), in collaboration with Fondazione Santa Lucia in Rome, Italy, have published details of how a class of drugs called “HDACis” drive muscle-cell regeneration in the early stages of dystrophic muscles, but fail to work in late stages. [...]

Penicillin Redux: Rearming Proven Warriors For The 21st Century

Penicillin, one of the scientific marvels of the 20th century, is currently losing a lot of battles it once won against bacterial infections. But scientists at the University of South Carolina have just reported a new approach to restoring its combat effectiveness, even against so-called “superbugs.” Bacteria have been chipping away at the power of [...]

Studies Show Lab-Grown Body Parts Working Well

In this photo issued by Wake Forest Institute for Regenerative Medicine and taken in April 2014, Yuanyuan Zhang, M.D., Ph.D, assistant professor at the Institute, demonstrates the process to engineer a vaginal organ in a laboratory in Winston Salem, N.C. Scientists report in two separate studies they have made vaginas and part of the nose, providing more evidence that growing organs in the laboratory is possible. Researchers have previously made windpipes, bladders, tear ducts and other organs in the lab. The two latest papers were published online Friday April 11, 2014 in the journal, Lancet. (AP Photo/WFBMC Photography)

Two new studies describe the latest achievements in growing body parts in a lab and transplanting them into people, this time with nostrils and vaginas. Windpipes, bladders, blood vessels and other structures have previously been created in part from a patient’s own cells and then implanted. Eventually, scientists hope to tackle more complicated things like [...]