An experimental, lab-made molecule was able to stick to certain inflammatory proteins and reduce acute breathing problems among people with a type of moderate-to-severe asthma, according to researchers at the University of Pittsburgh School of Medicine. Their findings were published today in the New England Journal of Medicine, coinciding with their presentation of the study in Philadelphia at the annual meeting of the American Thoracic Society.
Recent estimates suggest that 24.6 million Americans have asthma, and 10 to 20% of them don’t have optimal control of their symptoms despite modern medications, said senior author Sally Wenzel, MD, professor, Division of Pulmonary, Allergy and Critical Care Medicine (PACCM), Pitt School of Medicine, and director, University of Pittsburgh Asthma Institute at UPMC/University of Pittsburgh School of Medicine. Effective treatment of persistent, moderate-to-severe asthma has been challenging.
“We suspect that there are different underlying causes that lead to the clinical syndrome of asthma, so different treatment approaches are likely needed depending on what type of asthma a patient has,” she said. “A one-size-fits-all strategy might not, in fact, work for everyone.”









May 21st, 2013
John Buck












